Understanding of TRPV1 in Pain Grows

Pain Medicine News – Understanding of TRPV1  in Pain Grows, May Lead to Future Treatments

Research conducted at the University of California, San Francisco (UCSF) has shed new light on the transient receptor potential cation channel subfamily V member 1 (TRPV1) protein, which plays a significant role in pain perception, providing key details that ultimately may inform the development of new drugs for the treatment of chronic pain conditions.

a range of pain-inducing toxins and inflammatory compounds (including capsaicin and vanilloids) activate the protein, thus making it a potential therapeutic target.

“In that this model comes from capsaicin research, these therapies will likely be topical, and I suspect that postherpetic neuralgia and perhaps some forms of peripheral neuropathy will be the conditions where this may be most applicable. There is a stable research model now available.


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