Complex Regional Pain Syndrome (CRPS) is serious condition that affects a limb following an accident or operation. Researchers in the new study reported that they have successfully transferred antibodies from the serum of patients with CRPS to mice, causing many of the same symptoms to be replicated.
The findings of this study hint at a cause for it – harmful serum-autoantibodies – and raise the possibility of finding a treatment. In mice injected with the antibodies from CRPS sufferers, there was significantly more swelling of the affected limbs compared to mice injected with antibodies from healthy volunteers.
It’s quite possible that CRPS is caused by a fault in the immune system. This study seems to pinpoint the cause as autoantibodies, and by examining this area further we can look to develop a cure,