Hyperalgesia: No Reason to Stop or Reduce Opioids – May 30, 2017 – by Forest Tennant M.D., Dr. P.H.
One of the excuses that some health practitioners are using to stop opioids is to claim a patient has hyperalgesia (HA).
This is a most dishonest, devious, and dangerous ploy.
First, the definition of hyperalgesia is simply that a stimulus such as hitting your thumb with a hammer is more painful than usual.
Second, there is no way to measure or quantify the presence of HA in a chronic pain patient who takes opioids.
Practitioners who claim that a chronic pain patient has HA usually do so because they don’t like the dosage that a patient must take to relieve pain or they have a bias against opioids.
Some practitioners are actually telling patients that HA is harming them, and that their pain will improve or even go away if they stop opioids!! This dishonesty and deviousness may go further.
Once off opioids, the practitioner may recommend that a patient have expensive, invasive or unneeded procedures.
Danger may come with abrupt cessation of opioids in a severe chronic pain patient. There may be a combined or dual result of a severe pain flare along with severe opioid withdrawal symptoms.
This combined effect may result in a stroke, heart attack, psychosis, or adrenal failure. Some patients may commit suicide.
All who read this need to know that many expert pain specialists either do not believe that HA even exists or that it is irrelevant to clinical practice.
In other words, if a certain dosage of opioids is effective, continue treatment with opioids. There is no reason to stop or reduce opioids just based on HA.
Any time a patient is told they have HA and should stop or reduce opioids, they and their family or advocate should ask the following questions of the prescribing practitioner:
- What test or evaluation did you do to determine that I have HA?
- If I do have HA, what damage is it doing? (Show me some studies!!)
- When did I get HA? (Nothing has change in some time!)
- I’ve heard that HA may be the result of too much neuroinflammation or hormone deficiencies? Don’t I need to be tested for these?
- If I stop or reduce opioids and still have some pain, what are my alternatives? (Will you return me to my original opioid dosage?)
The author’s personal recommendations are:
(1) If your opioids don’t seem to be as effective as they once were, get a hormone panel blood test. I’ve seen many patients boost their opioid effect by replenishing pregnenolone, testosterone, estradiol, or another hormone that has diminished.;
(2) If you wish to reduce or stop your opioids, reduce your dosage about 5% a month. By slowly tapering you may be able to greatly reduce or even stop opioids.
Please inform all parties that HA is not, per se, a reason to stop or reduce opioids.
if you reduce or stop opioids,
what is your alternative, and,
if the alternative doesn’t work,
what will you do?