Anti-inflammatory drugs ‘no better than placebo’ for back pain: study – ABC News (Australian Broadcasting Corporation) – By medical reporter Sophie Scott and National Reporting Team’s Rebecca Armitage – Feb 2017
“Compared with placebo, non-steroidal anti-inflammatory drugs (NSAIDs) do not provide a clinically important effect on spinal pain,” Associate Professor Manuela Ferreira said.
And below you can read about a study showing that chiropractic is as effective as NSAIDs (anti-inflammatories). So, NSAIDs and chiropractic are both only as effective as a placebo.
Researchers found six patients had to be treated with anti-inflammatory drugs for one patient to achieve a clinically important benefit in the short-term.
And the drugs come with side effects.
Earlier research by the George Institute found paracetamol was also ineffective for back pain.
“When this result is taken together with those from recent reviews on paracetamol and opioids, it is now clear that the three most widely used, and guideline-recommended medicines for spinal pain do not provide clinically important effects over placebo,” she said.
Researchers found patients taking anti-inflammatories were more likely to have side effects, such as stomach ulcers and bleeding.
Senior research fellow at the George Institute for Global Health, Gustavo Machado said painkillers, such as anti-inflammatories, were not the answer to back pain.
“Millions of Australians are taking drugs that not only don’t work very well, they’re causing harm,” he said.
“We need treatments that will actually provide substantial relief of people’s symptoms.”
Spinal Manipulation for Low Back PainComparable to NSAIDs – July 18, 2017
Spinal manipulation therapy was shown to have modest improvements on pain and function at up to six weeks in patients with acute low back pain (LBP), according to a study published in JAMA (2017;317:1451-1460).
Moreover, the therapy was associated with only “temporary minor musculoskeletal harms,” according to the researchers.
Paul G. Shekelle, MD, PhD, of the VA West Los Angeles Medical Center, and his colleagues conducted a review and meta-analysis of previous studies to assess the efficacy and safety of spinal manipulation compared with other nonmanipulative therapies for adults with acute LBP (six weeks or less).
After analyzing 26 eligible randomized clinical trials (RCTs), the researchers found 15 trials (n=1,711) provided moderate evidence that spinal manipulation showed statistically significant improvements in pain.
Twelve RCTs (n=1,381) demonstrated moderate evidence that spinal manipulation was significantly linked to improvements in function.
No RCTs reported any serious adverse events.
The authors wrote that the benefits of spinal manipulation for acute LBP were comparable to those seen with nonsteroidal anti-inflammatory drugs, according to the Cochrane review on this topic.