Being Judged: The Swinging Pendulum and Pain Mgmt

Being Judged:The Swinging Pendulum and Pain Management  Kathleen Hoffman on Apr 10, 2017

Did you know that before the year 2000, poor pain management was called a major medical problem and was synonymous with poor medical care in the US?

On January 1, 2001, Congress declared 2001 to 2010 the Decade of Pain Control and Research.

Assuring that effective pain management occurred in hospitals, in 2003, the Joint Commission on Accreditation of Healthcare Organizations (JCOH) added pain management criteria to the requirements they establish for hospital accreditation.  

Pendulum swings

Now, we are having an “opioid crisis.” The pendulum has swung back: instead of under medicating for pain, the concern is over medicating for pain.

 Why this pendulum swing?  

The answer has to do with the nature of pain, the painkillers our bodies naturally produce and our efforts to manage pain.

Subjective measures

Pain is measured subjectively because we haven’t figured out how to measure it any other way.   Improving pain assessment tools has been a huge challenge.

Pain is complicated. It is both physical and emotional.

All over our body there are nociceptors, sensory neurons (nerve cells) that respond to negative stimuli.

The signals from these receptors travel to the spinal cord and then on to the brain.  

Interestingly, the places where pain messages are sorted out in the brain are the same places from which basic emotions, like anger and fear, are experienced.

Neurotransmitters

Pain research has focused on neurotransmitters: the chemicals involved in transmitting messages or signals from one neuron to another. The process involves passing signals through release of these chemicals in small packages (called vesicles) into the synapses (the space between the neurons).

neuron receiving the message has a receptor protein on its surface that binds to the chemicals. The receptors have two responses, to open and move the message forward (excitatory receptors) or to block the message from moving forward (inhibitory receptors).   TrpV1 is an excitatory receptor that is associated with feeling pain from heat.   Another excitatory neurotransmitter is glutamate which has been implicated in persistent pain. Finding chemicals that will block glutamate will be instrumental in reducing pain.

Opioids are neurotransmitters as well.  

Our bodies produce these pain killers naturally: an example of a natural opioid in our body is the endorphins associated with the runner’s high.

Morphine, either made synthetically or from poppies, is a pain medication that is like our bodies’ natural opioids.  Because morphine can activate the opioid transmitters of the body, it is a powerful pain killer. But because it is so like what is produced by our bodies, it is also very addictive. *

Pain Is Different For Everyone

Everyone’s  experience with pain is unique.  Our different genetic make-up affects our pain sensitivity. Research has even identified genes involved in the process of feeling pain.

In 2011, the Institutes of Medicine estimated that over 100 million people in the US suffer from chronic pain.   Sadly, the IOM also identified a cultural bias in the US against people who have chronic pain: specifically,

those with chronic pain are seen as weak and thought to be lying about their pain.

In a forum where medical students ask practicing physicians questions on how to treat patients, the comments from physicians exemplify this cultural bias.

  • One medical student wroteHow do you handle these patients? They come in saying intractable abdominal pain “I haven’t been able to eat or drink in a week!” and are generally on an absurd amount of pain medication. Then you get labs/imaging and there is nothing out of line. I hate these patients with a passion.”
  • Another wroteIt’s [gastroparesis] largely a disease of the young entitled wuss-crowd that has always thought that they could destroy themselves with cigarettes, alcohol, narcotics, high-fructose corn syrup, fast-food, and never have to deal with the consequences.
  • Still another believed that these patients want to “get put into a narcotic haze and have no responsibilities.”
  •  As Melissa Van Houton wrote, “It is absurd that we are put in a position where we have to FEAR going to an ER or a doctor because we might be mocked!”

In her 2014 post published in Experts by Experience, Dawn Nellor, a patient with pulmonary sarcoidosis and chronic pain describes her experiences in this way, “The behavior of past appointments with physicians…have numbed me to their raised eyebrows and the “look-away” that represents disbelief.”  

As Judy Stone, writing about patients with rare disease in Forbes says, “A huge burden for patients with chronic pain and fatigue is being told that they are crazy.”

The post Not My Problem Healthcare is a description of someone with two rare diseases who wasn’t believed.

As Felice J. Freyer wrote in a 2016 story for the Boston Globe called, The Other Side of America’s War on Opioids,

“As federal and state regulators rush to curtail access to drugs that have claimed thousands of lives, the rules they’ve enacted fall hard on people who legitimately need relief from pain [emphasis added]. In an atmosphere of heightened concern about opioids, patients in pain face reluctant doctors, wary pharmacists, and the frequent demand to prove that they are not addicts.”

Take Away

Since no one experiences pain in the same way, it might be time to take a deep breath and ask ourselves one question.  

Why do we blame victims of pain who need our help?

*Recent research has shown that glial cells, which are cells of the nervous system that support neurons, are involved in every experience of pain, including the experience of chronic pain.  Glials cells have receptors called TLR4 that are activated when pain is experienced.  Opioids also activate the TLR4 receptors. When the TLR4 is blocked, the analgesic action of drugs like morphine can be increased.

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