Alterations to cell metabolism in connective tissues of the knee after ovariohysterectomy in a rabbit model: are there implications for the postmenopausal athelete? – PubMed – NCBI Br J Sports Med. 2010 Sep;
Participation in regular exercise and athletic activities across the lifespan is encouraged to maintain the cardiovascular and musculoskeletal systems and general wellbeing.
Before the menopause there is an increased risk of anterior cruciate ligament (ACL) injuries in female athletes, whereas there is an increased risk of joint diseases such as knee osteoarthritis after the menopause.
Although there are few data regarding alterations in individual connective tissues of the knee in humans either before, during or after the menopause, it is possible to assess changes in experimental models following surgical menopause. Continue reading
Choosing Acceptance Over Fighting Ehlers-Danlos, Mitochondrial Disease | The Mighty | Apr 2017 | By Maria Stebbins
“She’s a real fighter.”
I have such mixed feelings about that phrase. Yes, my body presents plenty of challenges, which I face constantly. However, the language equating this life to a violent war doesn’t quite fit.
You see, genetic conditions can’t be vanquished like nasty infections. For better or worse, they just…exist. I wrestle with treating individual symptoms and eking out a little more energy, but the root of all that won’t retreat under heavy fire.
If I’m fighting a battle, it’s against myself. Maybe it’s just me, but I’d prefer not to spend my days at war with myself, physically or spiritually. Continue reading
My Body’s Bad Glue | ENTROPY – – December 26, 2016
This is a wonderful essay linking the physical “disconnectedness” of EDS to a psychic feeling of disconnection from the self.
I have Ehlers-Danlos Syndrome, which means my body has bad glue.
My glue, an amorphous, drunk blob or cloud, playing tricks, getting things all wrong, incapable of indicating what is real. My genes, speaking to my body in the wrong language, refusing to bind me, utterly stupid in regards to what level of adhesion properly constructs a body. Continue reading
Hypermobility Syndromes Association » Hormones & Hypermobility – By Alan Hakim, June 9, 2013
A hormone is sometimes described as a ‘chemical messenger’ that is secreted from a gland, circulates through the bloodstream and, finally, reaches the organ at which it is directed where it exerts its effect.
Although there are many types of hormones, all of different structures, two main groups are relevant to hypermobility.
Firstly are the corticosteroids, which comprise three families: Continue reading
Orthostatic Intolerance and Postural Orthostatic Tachycardia Syndrome in Joint Hypermobility Syndrome/Ehlers-Danlos Syndrome, Hypermobility Type: Neurovegetative Dysregulation or Autonomic Failure? – Biomed Res Int. – Feb 2017 – free full-text PMC article
Joint hypermobility syndrome/Ehlers-Danlos syndrome, hypermobility type (JHS/EDS-HT), is a hereditary connective tissue disorder mainly characterized by
- generalized joint hypermobility,
- skin texture abnormalities, and
- visceral and vascular dysfunctions,
- also comprising symptoms of autonomic dysfunction.
This study confirms the abnormal cardiovascular autonomic profile in adults with JHS/EDS-HT and found the higher baroreflex sensitivity as a potential disease marker and clue for future research. Continue reading
The association between muscle strength and activity limitations in patients with the hypermobility type of Ehlers–Danlos syndrome: the impact of proprioception: Disability and Rehabilitation: 24 Jun 2016 – Free full-text article
The patients diagnosed with Ehlers–Danlos Syndrome Hypermobility Type (EDS-HT) are characterized by pain, proprioceptive inacuity, and muscle weakness, potentially leading to activity limitations.
Twenty-four EDS-HT patients were compared with 24 controls.
- Muscle strength is associated with activity limitations in EDS-HT patients.
- Joint proprioception is of influence on this association and should be considered in the development of new treatment strategies for patients with EDS-HT.
L-carnitine supplementation for the management of fatigue in patients with hypothyroidism on levothyroxine treatment: a randomized, double-blind, placebo-controlled trial– Endocrine Journal – 2016 – free full-text
Hypothyroid patients experience fatigue-related symptoms despite adequate thyroid hormone replacement.
Thyroid hormone plays an essential role in carnitine-dependent fatty acid import and oxidation.
We investigated the effects of L-carnitine supplementation on fatigue in patients with hypothyroidism. Continue reading
Combating Wear and Tear on Our Collagen – University of Utah – Mar-2017
This article explains much of what causes our pain from EDS. With our defective collagen, even small stresses can cause “sub-failure damage” which accumulates until the tissue fails completely.
University of Utah bioengineers detect early signs of damage in connective tissues such as ligaments, tendons and cartilage
By the time someone realizes they damaged a ligament, tendon or cartilage from too much exercise or other types of physical activity, it’s too late. The tissue is stretched and torn and the person is writhing in pain.
Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement – 2014 Dec – free full-text PMC article
related to The Fibromyalgia-Thyroid Connection
Background: A number of recent advances in our understanding of thyroid physiology may shed light on why some patients feel unwell while taking levothyroxine monotherapy
The purpose of this task force was to review
- the goals of levothyroxine therapy,
- the optimal prescription of conventional levothyroxine therapy,
- the sources of dissatisfaction with levothyroxine therapy,
- the evidence on treatment alternatives, and
- the relevant knowledge gaps.
This document is intended to inform clinical decision-making on thyroid hormone replacement therapy; it is not a replacement for individualized clinical judgment. Continue reading
The Fibromyalgia-Thyroid Connection. If your TSH thyroid test is normal, you better read this… – National Pain Report – By Donna Gregory Burch – April 4, 2017
Did you know that thyroid conditions are routinely misdiagnosed as fibromyalgia?
I’m sure most of our doctors ran a TSH test to check our thyroid function since hypothyroidism is one of the many conditions that are supposed to be ruled out before diagnosing fibromyalgia.
That’s because the TSH test, the test most commonly used by doctors to diagnose thyroid issues, is a poor indicator of overall thyroid health.
It takes a much more comprehensive approach to testing and clinical expertise to properly diagnose thyroid disorders. Continue reading