Specific impairments within six large-scale brain networks during drug cue exposure, decision-making, inhibitory control, and social-emotional processing are associated with drug addiction behaviors, according to a systematic review of more than 100 published neuroimaging studies by experts at the Icahn School of Medicine at Mount Sinai and published Wednesday, June 6 in the journal Neuron.
Drug addiction is a disorder that encompasses not only excessive drug-seeking and taking, but also fundamental changes in cognition and emotional processing. Continue reading
This piqued my curiosity, so I followed the link and found an interesting story of the “old days” of heroin in New York City in 1972, how the cost and scarcity of heroin led to dealers adding quinine.
This is strikingly similar to what we see now in 2018 when dealers are adding much cheaper and much more powerful fentanyl to all kinds of other street drugs: heroin, cocaine, and even counterfeit pills (made with the same pill presses the pharmaceutical industry uses). Continue reading
- Drug Overdose
Tom Petty died from, according to the New York Times headline (link is external), an “Accidental Drug Overdose.”
Here’s the coroner’s list of the drugs found in Petty’s system:
- acetyl fentanyl and
- despropionyl fentanyl.
Introduction: Addiction and Brain Reward and Anti-Reward Pathways – free full-text article /PMC4549070/ – Aug 2011
This is a long and detailed article explaining at length how pain and addiction manifest in neurological processes in various areas of the brain.
It also contradicts the belief that opioids cause addiction, which has motivated the anti-opioid crusaders to make life a hell on earth for pain patients. (see Pain Patients Left to Suffer in ‘Hell on Earth)
Can One Induce Addiction
by Long-Term Treatment of Pain with Opiates? Continue reading
Addiction is not a predictable result of opioid prescribing – NEJM – Mar 2016 – Nora D. Volkow, M.D., and A. Thomas McLellan, Ph.D.
Anti-opioid crusaders in the media insist that any opioid medications can almost immediately cause addiction in any person exposed to them.
However, as head of NIDA (the National Institute on Drug Abuse at the NIH), Dr. Volkow has more expertise in addiction than the self-anointed “experts” broadcasting false narratives about opioid addiction (and often trying to sell addiction-recovery programs). Dr. Volkov makes very clear the differences between dependence, tolerance, and addiction.
There is lingering misunderstanding among some physicians about the important differences between physical dependence and addiction. Continue reading
A philosopher explains why addiction isn’t a moral failure.
Methadone and buprenorphine, the most effective medication-assisted treatments, are “crutches,” in the words of felony treatment court judge Frank Gulotta Jr.; they are “just substituting one opioid for another,” according to former Health and Human Services Secretary Tom Price.
Most of us have been trained to use more forgiving language when talking about addiction. We call it a disease. We say that people with addiction should be helped, not blamed. But deep down, many of us still have trouble avoiding the thought that they could stop using if they just tried harder. Continue reading
Mayo Clinic Taking Steps to Tackle Opioid Crisis | KAALTV.com – April 19, 2018 – ABC 6 News
A new Mayo Clinic survey is shedding light on opioid use after surgery and whether or not some patients are being over-prescribed. The survey found about 92 percent of patients keep their leftover pills.
They are trying to prove opioids are over-prescribed but notice this actually proves that 92% of patients receiving opioids did not get addicted.
She said a Mayo Clinic survey found 63 percent of the pain medicines being prescribed to patients after surgery go unused.
No addicted person would be able to leave opioid pills unused, proving again that people taking opioids to treat pain rarely become addicted.
Mady Ohlman was 22 on the evening some years ago when she stood in a friend’s bathroom looking down at the sink.
“I had set up a bunch of needles filled with heroin because I wanted to just do them back-to-back-to-back,” Ohlman recalled. She doesn’t remember how many she injected before collapsing, or how long she lay drugged-out on the floor.
She wanted to be dead, she said. Continue reading
American hoarders helping push up rates of opioid addiction, overdose – Tim Mullaney, special to CNBC – Sept 2017
Your medicine cabinet could be contributing to the opioid epidemic.
What happened the last time you were prescribed an opioid? If you’re like most people, you didn’t finish them — and didn’t dispose of them — in effect, making you a potential source of illicit drugs and addiction that has been exploding across America.
What utter nonsense. Recent data shows that opioid prescriptions are already at a 10-year low. (See Overdoses Increasing While Opioid Rx at 10-year Low) Continue reading
I-TEAM: Opioid addiction versus dependency – By: George Knapp – Feb 22, 2018
Millions of chronic pain patients, already living in agony because of disease or injuries, now live in fear that their medicine will be taken away because they’ve been stigmatized as drug addicts.
Ninety percent of those who die of overdoses use illicit drugs.
Why is this still invisible to policy-makers? I don’t understand how any reasonably intelligent person could look at the CDC’s overdose numbers and not notice that overdoses are driven by illicit fentanyl, not prescription medication. Continue reading