Tag Archives: addiction

The Science of Drug Use and Addiction

The Science of Drug Use and Addiction: The Basics | National Institute on Drug Abuse (NIDA) July 2018

Here’s what our own government’s experts of the National Institute of Drug Abuse (NIDA) believe about addiction. It’s an amazingly realistic appraisal, very different from PROP’s anti-opioid rhetoric.  

Addiction is defined as

  • a chronic, relapsing disorder characterized by
  • compulsive drug seeking,
  • continued use despite harmful consequences, and
  • long-lasting changes in the brain.   Continue reading

Can You Really Be Addicted After Just One Dose?

Can You Really Become Addicted to a Drug After Just One Hit? – VICE – by Matilda Whitworth |Oct 22 2015

The idea that one toke on a crack pipe destroys your life is popular, but it contradicts what we know about brain chemistry.

You know the story. The one that says some drugs are so enjoyable, so insidious, that just one try will get you hooked. And you’d be forgiven for believing this as the media really backs the theory.

  • “The Danger In Just One Hit of Cocaine,” reports the Daily Mail.
  • Official: 1-Hit Addiction to Meth No Myth,” announces the Times Daily.
  • “It Only Took One Hit to Get Hooked,” writes news.com.

But is it actually true? Can a person become addicted to a drug after using it a single time? Continue reading

Misconceptions about Opioid Abuse in Chronic Pain

Opioid Abuse in Chronic Pain — Misconceptions and Mitigation Strategies — NEJM – Nora D. Volkow, M.D. [Director of the National Institute on Drug Abuse (NIDA)], and A. Thomas McLellan, Ph.D. – Mar 2016 – free full-text article

I’m reposting this classic paper, which ironically came out the same month as the CDC Guidelines. Those guidelines showed zero understanding of the latest research and facts about opioid abuse and chronic pain that our own government is aware of.

Chronic pain not caused by cancer is among the most prevalent and debilitating medical conditions but also among the most controversial and complex to manage.

The urgency of patients’ needs, the demonstrated effectiveness of opioid analgesics for the management of acute pain, and the limited therapeutic alternatives for chronic pain have combined to produce an overreliance on opioid medications in the United States, with associated alarming increases in diversion, overdose, and addiction   Continue reading

DSM-V splits drug dependence by specific drug

With what we know about addiction these days, it makes no sense to split the “substance dependence” diagnoses into groups by the specific drug. Addiction happens when the brain habituates to a malfunction of satisfying cravings despite increasing harms.

It’s the users that become addicted and have a problem, not the substance!

Wikipedia information on DSM-5

The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) is the 2013 update to the Diagnostic and Statistical Manual of Mental Disorders, the taxonomic and diagnostic tool published by the American Psychiatric Association (APA).   Continue reading

Very Little Opioid Misuse in Military Patients

Only 1 in 4 troops have an opioid prescription in a given year – By: Karen Jowers – Dec 2018

Nearly 1 in 4 active-duty service members had at least one prescription for an opioid at some point in 2017, according to Defense Department research.

About 1 in 4 retirees also had at least one opioid prescription.

That doesn’t necessarily equate to opioid addiction. Opioids are prescribed for moderate-to-severe pain after surgery, injury, or for pain from conditions such as cancer.
Continue reading

The trouble with heroin


I found this intimate description of heroin withdrawals so compelling I began to squirm as I read (. I’m sharing it here so those of us taking opioids for pain can understand the dilemma of those who begin taking opioids for recreation. What starts as “fun” quickly turns into a desperate compulsion to avoid truly unbearable misery.

A lot of people are physically sick when taking gear [heroin] for the first time. The body is reacting naturally by dispelling poison from its system, heroin is a poison to the body. The body quickly adapts to regular heroin intakes, the speed of the addiction is revealing, after a few days your body can tolerate and then require regular top ups to feed the tolerance.   Continue reading

Opioid Withdrawal Not Deadly? Wrong

Opioid Withdrawal Not Deadly? Wrong | Medpage Today – by Jeffrey E. Keller, MD Nov 2018

I’ve seen enough patients withdrawing from opioids [in a jail medical practice] that I think I am reasonably knowledgeable on the topic. Because of this, I was quite surprised when I ran across this sentence in a recent edition of The Medical LetterOpioid withdrawal is not life-threatening.”

The problem is that although this sentence seems quite self-assured, it is flat out wrong. In fact, it is not just wrong; it is also dangerous.

People do die from opioid withdrawal. I know of several such cases from my work with jails.   Continue reading

Media, Politicians Unaware that Addiction != Dependence

Are Media and Politicians Aware That Addiction and Dependence Are Not the Same Thing? – September 18, 2018 – Jeffrey A. Singer

Hardly a day goes by without a report in the press about some new addiction.

One gets the impression that life is awash in threats of addiction. People tend to equate the word “addiction” with “abuse.” Ironically, “addiction” is a subject of abuse.

The American Society of Addiction Medicine defines addiction as a

  • “chronic disease of brain reward, motivation, memory and related circuitry…characterized by
  • the inability to consistently abstain,
  • impairment in behavioral control,
  • craving” that continues despite resulting destruction of relationships, economic conditions, and health

Continue reading

I’ts an Overdose Epidemic not an Opioid Epidemic

Why there’s an overdose epidemic — in two graphs – STAT – By Hawre Jalal and Donald S. Burke – September 20, 2018

Here two of the authors write more about their recent study of the “Overdose Epidemic”:

The “overdose epidemic” that so many Americans are talking about isn’t really a single epidemic. It’s actually several of them, something we began exploring when we graphed the yearly counts of overdose deaths for the last 40 years.

It turns out that, when totaled, these sub-epidemics trace a nearly perfect exponential growth curve. For four decades, overdose deaths have been growing, doubling about every eight years.   Continue reading

Maker of OxyContin granted patent for addiction treatment

Richard Sackler, member of family behind OxyContin, was granted patent for addiction treatment – By Andrew Joseph @DrewQJoseph – Sept 2018

Again, truth proves to be stranger than fiction. Apparently, there’s money to be made from both leading into and leading out of addiction, so I suppose it’s natural that a pharmaceutical company would follow the money.

A member of the family that owns Purdue Pharma — which is being sued by more than 1,000 jurisdictions for its alleged role in seeding the opioid crisis with its pain medication OxyContin — has been awarded a patent for a treatment for opioid use disorder.

Critics told the FT that they were disturbed that the patent could enable Sackler to benefit financially from the addiction crisis that his family’s company is accused of fueling.   Continue reading