People With Advantageous Personality Traits Have More Nerve-Fibre Insulation (Myelination) In Key Brain Areas – By Christian Jarrett – Jan 2019
I’ve always wondered why a physical defect of connective tissue, as we have with EDS, is linked to anxiety (my life’s greatest plague after pain). This article shows that a lack of good insulation (myelin) around brain neurons can lead to distinct negative personality traits.
Researchers are getting closer to understanding the neurological basis of personality. For a new paper in the Journal of Personality, Nicola Toschi and Luca Passamonti took advantage of a recent technological breakthrough that makes it possible to use scans to estimate levels of myelination in different brain areas (until fairly recently this could only be done at postmortem).
This makes me wonder if our defective connective tissue might also lead to defective insulation around our neurons, allowing some signals to “leak” to adjacent areas. Could that explain my general “mood instability” as well? Continue reading
Emotional Impact of Pain | Pain Management & Understanding | Arthritis.org
Although it may feel like it’s coming from your joints, pain – particularly the chronic pain common to arthritis – is also an expression of your state of mind.
If you’re depressed or anxious, you’ll very likely hurt more than when your mood is lighter or more balanced.
The crucial distinction is that depression or anxiety will only worsen *pre-existing* pain, not create new pain.
The fact that pain itself is depressing and worrying only makes the problem worse. Continue reading
Urine Test Could Diagnose Depression, Anxiety | American Council on Science and Health – By Alex Berezow — September 29, 2018
This seems like a hugely significant discovery that could save the healthcare system a lot of money treating people for suspected mental disorders when there is not psychological problem at all.
Depression and anxiety are not always easy to detect. The obvious symptoms, such as persistent sadness or worry, may not be present.
Instead, a person may exhibit insidious symptoms, like chronic indecision or excessive sleepiness. Diagnosis usually requires a psychologist. Besides being time consuming and inconvenient, diagnostic criteria are rather subjective. Continue reading
Commentary: We must understand the causes of anxiety and suicide – By Perry G. Fine – September 16, 2018
Although the U.S. Centers for Disease Control and Prevention asserts that there is no single cause that can be attributed to this national trend, we know that serious, life-impacting anxiety, depression and chronic pain are at an all-time high and strongly correlated with suicide attempts.
The 25 percent increase in the suicide rate has mirrored similar upswings in other harmful behaviors and chronic illnesses.
These include parallel increases in diabetes and obesity-related mortality, gun violence deaths and drug overdose fatalities. Continue reading
Why do people kill themselves? – KevinMD.com – March 2017 – by Greg Smith, MD
I use an ongoing spreadsheet to keep track of and to report my demographics and stats for each telepsychiatry consult shift I do. We have now gone over thirty thousand consults as a group.
It never ceases to amaze me, as I fire up my computer, log on to my systems and bring up the spreadsheet for the shift ahead, that one column is remarkably uniform and consistent, sometimes for days at a time: SI.
SI stands for suicidal ideation. And that is one of the most common chief psychiatric complaints we see in the emergency department. Continue reading
Anxiety and joint hypermobility: An unexpected association – Current Psychiatry. 2018 April
Joint hypermobility syndrome (JHS)—also known as Ehlers-Danlos type 3–hypermobile type (hEDS)—is a poorly recognized connective tissue disorder characterized by increased joint laxity that may affect 10% to 25% of the general population.
Researchers are increasingly recognizing an association between JHS/hEDS and psychiatric symptoms and disorders, specifically anxiety.
In this review, we describe the clinical presentation of JHS/hEDS, propose a new “Neuroconnective phenotype” based on the link between anxiety and JHS/hEDS, and discuss factors to consider when treating anxiety in a patient who has JHS/hEDS. Continue reading
Brain structure and joint hypermobility: relevance to the expression of psychiatric symptoms – Br J Psychiatry. 2012 Jun – free full text /PMC3365276/
This is not a new article, but a thorough scientific survey of the brain differences seen in people with hypermobility (which is usually undiagnosed EDS). This was the beginning of my understanding that EDS is not just a physical issue, but also affects our minds.
To me, it makes sense that the same instability (lack of balance, tendency to extremes) found in our bodies would also be represented in our brains/minds.
Joint hypermobility is overrepresented among people with anxiety and can be associated with abnormal autonomic reactivity. Continue reading
Below are three PubMed studies from 2015 about the detrimental effects of EDS on the mind/brain:
Joint hypermobility and the heritable disorders of connective tissue: clinical and empirical evidence of links with psychiatry. – PubMed – NCBI – Gen Hosp Psychiatry. 2015 Jan-Feb
OBJECTIVE: The heritable disorders of connective tissue (HDCTs) are a group of genetic disorders affecting connective tissue matrix proteins. Continue reading
Below are 4 articles from PubMed that show EDS is associated with anxiety, depression, and other disorders of the central nervous system, like fibromyalgia and irritable bowel syndrome.
Connective tissue is *everywhere* in our bodies (yes, including our bones), so the defects in our body tissues extend to the brain as well.
I’ve been plagued by periods of desperate anxiety for the last decade and periods of suicidal depression for all my adult life, so I’m not surprised that the instability and slackness of our bodies are also manifested in our psychology. My moods never feel stable and can easily be derailed.
The number of possible EDS symptoms seems infinite… Continue reading
Pain as a risk factor for common mental disorders. Results from the Netherlands Mental Health Survey and Incidence Study-2: a longitudinal, population-based study – PAIN: April 2018
I’ve read too many articles that insinuate chronic pain arises from pre-existing mental issues and claim the focus should be on the mental disorder more than the pain. (This is part of the popular idea of “catastrophizing“)
But this article makes it clear that pain leads to “psychological” disorders, not the other way around as many would like us to believe. It is known that the unremitting assault by pain is a form of chronic stress that damages brain structure and connectivity. Continue reading