Tag Archives: anxiety

Link Between Breathing and Anxiety

The breathing conundrum – interoceptive sensitivity and anxiety  2013 Oct – free full-text PMC article

This review focuses on the relationship between breathing and anxiety.

Several anxiety disorders have been associated with

  • altered breathing,
  • perception of breathing and
  • response to manipulations of breathing.

Both clinical and experimental research studies are reviewed that relate breathing dysfunctions to anxiety.   Continue reading

Emotion processing in joint hypermobility

Emotion processing in joint hypermobility: A potential link to the neural bases of anxiety and related somatic symptoms in collagen anomalies. – PubMed – NCBI – Eur Psychiatry. 2015 Feb

Joint hypermobility syndrome (JHS) has repeatedly been associated with anxiety and anxiety disorders, fibromyalgia, irritable bowel syndrome and temporomandibular joint disorder.

However, the neural underpinnings of these associations still remain unclear.

This study explored brain responses to facial visual stimuli with emotional cues using fMRI techniques in general population with different ranges of hypermobility.   Continue reading

Interoceptive sensitivity and anxiety

The breathing conundrum – interoceptive sensitivity and anxiety – Oct 2013 – free full-text PMC articlle

Various controlled breathing practices seem to have powerful effects on the nervous system, probably through stimulation of the vagus nerve.

This review focuses on the relationship between breathing and anxiety.

Several anxiety disorders have been associated with

  • altered breathing,
  • perception of breathing and
  • response to manipulations of breathing.

Continue reading

Working Memory Role in Emotional Regulation

When the going gets negative, recruit working memory — ScienceDaily — November 21, 2016

Working memory, the ability to process information, may play an important role in coping with negative life events, according to a new study by Dr. Tracy Alloway, associate professor of psychology at the University of North Florida.

“There is a growing body of research supporting the role of working memory in emotional regulation.”

We know that

  1. those with clinical depression have difficulties in suppressing irrelevant negative information, while
  2. those with high working memory are able to ignore negative emotions.   Continue reading

LInks between Chronic Pain, Anxiety, and Depression

Association of Depression and Anxiety Alone and in Combination with Chronic Musculoskeletal Pain in Primary Care Patients – Psychosom Med. 2008 Oct; – free full-text PMC article

To assess the relationship between depression and anxiety comorbidity on pain intensity, pain-related disability, and health-related quality of life (HRQL).


Pain is a significant public health problem, with a third (1) to more than half (2) of adults in population-based surveys suffering from chronic or recurrent pain.  

Pain is the most pervasive symptom reported in the community and primary care setting (3–5) and accounts for nearly 20% of all ambulatory visits in the US (6).   Continue reading

Link Between Chronic Pain and Anxiety

Study Reveals Connection between Chronic Pain and Anxiety – National Pain Report

New research reveals a little-understood connection between chronic pain and anxiety, and offers a potential target for treatment, according to a release from the University of Vermont.

University of Vermont (UVM) researchers published their findings as an Article in Press in Biological Psychiatry.  Their study revealed that increased expression of PACAP – a peptide neurotransmitter the body releases in response to stress – is also increased in response to neuropathic pain and contributes to these symptoms.

“Chronic pain and anxiety-related disorders frequently go hand-in-hand,” says senior author Victor May, Ph.D., professor of neurological sciences at the University of Vermont.  May and members of the research team found that PACAP was also highly expressed in women exhibiting PTSD symptoms, in a 2011 study.

While May and his colleagues saw an increase in anxiety-related behaviors in models of chronic pain, the anxious behavior and pain hypersensitivity were significantly reduced when a PACAP receptor antagonist – designed to block the response – was applied.  

Are Opioids the Next Antidepressant?

Are Opioids the Next Antidepressant? – The New York Times

ONE of the most painful experiences of being a psychiatrist is having a patient for whom none of the available therapies or medications work.

A while back, I was asked to do a consultation on just such a patient. This person had been a heroin addict in her early 20s. She had quit the opioid five years earlier, but her life was plagued with anxiety, apathy and self-doubt that prior treatments had not helped.

At the end of the session, almost as an afterthought, she noted with irony that the only time in her adult life when she had been able to socialize easily and function at work was when she had been hooked on heroin.   Continue reading

Women with ADHD: more mental health problems

Adult Women Diagnosed With ADHD May Face Increased Risk Of Mental Health Conditions, Suicidal Thoughts – Jul 21, 2016 –  By Dana Dovey

A new study has found a disturbing link between attention deficit hyperactivity disorder (ADHD) in women and serious mental and health conditions.

According to the research conducted by a team from the University of Toronto in Canada, one-third of women with ADHD have anxiety disorders, and almost half of this group has considered suicide.

The finding may cause us to re-evaluate the severity of ADHD in women and the true scope of its effects.   Continue reading

Mental disorders from chronic pain in adolescence

Chronic pain in adolescence and internalizing mental health disorderdepres: a nationally representative study : PAIN –  June 2016 – Abstract only

Chronic pain in childhood and adolescence has been shown to heighten the risk for depressive and anxiety disorders in specific samples in adulthood; however, little is known about the association between a wider variety of chronic pains and internalizing mental health disorders.   Continue reading

Anxiety and Endocrine Disease

Anxiety and Endocrine Disease – Richard C. W. Hall, M.D. Courtesy Clinical Professor of Psychiatry, University of Florida, Gainesville

Though this article is a bit old (from 2011, I believe) these findings have not been disputed and are still valid.

It is our goal in this article to review the literature and define those endocrinological diseases that often include anxiety states as part of their initial presentation or as a characteristic symptom seen during their course.

Understanding the mechanism by which anxiety develops as a routine part of these neuroendocrinological disorders may help us understand the organic basis of anxiety disorders.  Continue reading