Here are 3 studies on how estrogen can prevent muscle wasting and improve mitochondrial function.
Aging of the musculoskeletal system: How the loss of estrogen impacts muscle strength. – PubMed – NCBI – Jun 2019
Skeletal muscle weakness occurs with aging and in females this is compounded by the loss of estrogen with ovarian failure.
Estrogen deficiency mediates decrements in muscle strength from both
- inadequate preservation of skeletal muscle mass and
- decrements in the quality of the remaining skeletal muscle.
The Effects of Voluntary, Involuntary, and Forced Exercises on Brain-Derived Neurotrophic Factor and Motor Function Recovery: A Rat Brain Ischemia Model – free full-text /PMC3035657/ – Feb 2011
I was happy to find that what I have personally experienced has been proven to be true: forced exercise is not as beneficial as voluntary. Sometimes science actually proves our intuitions correct – surprise!
Stroke rehabilitation with different exercise paradigms has been investigated, but which one is more effective in facilitating motor recovery and up-regulating brain neurotrophic factor (BDNF) after brain ischemia would be interesting to clinicians and patients.
Physical Activity and Brain Health – free full-text PMC6770965/ – Genes (Basel). Sep 2019 – continued from Part 1
Exercise-Dependent Production of Dopamine, Endocannabinoids, and Opioids: Effects on Mood, Analgesia, and Happiness
In addition to an improvement of body fitness and learning and memory skills, it is well documented that PA (Physical Activity) can induce changes in the mental status, reducing anxiety and producing a general sense of wellbeing.
Moreover, it can induce analgesia.
Really? When I engage in physical activity, it’s usually a painful endeavor. If I didn’t enjoy some activities so very much, like hiking, bicycling, and dancing, I can’t imagine I’d have the will to do them.
Physical Activity and Brain Health – free full-text PMC6770965/ – Genes (Basel). Sep 2019
Physical activity (PA) has been central in the life of our species for most of its history, and thus shaped our physiology during evolution. However, only recently the health consequences of a sedentary lifestyle, and of highly energetic diets, are becoming clear.
It has been also acknowledged that lifestyle and diet can induce epigenetic modifications which modify chromatin structure and gene expression, thus causing even heritable metabolic outcomes.
About 50 years ago, scientists first learned that genetics has another layer, epigenetics. It matters not just what your genes are, but also on whether they are turned on or off. Continue reading
Muscle mass, muscle strength, functional performance, and physical impairment in women with the hypermobility type of Ehlers‐Danlos syndrome
This is a continuation of the previous post of Part 1, and picks up at the “Discussion” section:
This study demonstrates severely reduced quantitative muscle function and substantial impairment in physical function in patients with EDS‐HT compared to age‐ and sex‐matched controls.
muscle pain and muscle fatigue were omnipresent in the patient group, increased remarkably due to the muscle strength tests, and decreased very slowly after each test. Continue reading
Muscle mass, muscle strength, functional performance, and physical impairment in women with the hypermobility type of Ehlers‐Danlos syndrome – Rombaut – 2012 – Arthritis Care & Research – Wiley Online Library
Objective: To investigate
- lower extremity muscle mass,
- muscle strength,
- functional performance, and
- physical impairment
in women with the Ehlers‐Danlos syndrome hypermobility type (EDS‐HT).
This is exactly what I’ve been searching for: a study on muscle problems in EDS. Finally, I found some explanation of all the odd issues I’ve had with my muscles over the years. Continue reading
Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement – free full-text /PMC6241620/ – Dec 2018
The fascial system builds a three-dimensional continuum of soft, collagen-containing, loose and dense fibrous connective tissue that permeates the body and enables all body systems to operate in an integrated manner.
Injuries to the fascial system cause a significant loss of performance in recreational exercise as well as high-performance sports, and could have a potential role in the development and perpetuation of musculoskeletal disorders, including lower back pain. Continue reading
Stretching impacts inflammation resolution in Connective Tissue – Free full text – /PMC5222602/ – Jul 2017
I’m encouraged to learn that stretching has been shown to be very beneficial for sore muscles. not before exercise, but afterward.
Acute inflammation is accompanied from its outset by the release of specialized pro-resolving mediators (SPMs), including resolvins, that orchestrate the resolution of local inflammation.
We showed earlier that, in rats with subcutaneous inflammation of the back induced by carrageenan, stretching for 10 minutes twice daily reduced inflammation and improved pain, two weeks after carrageenan injection. Continue reading
Low Energy Production and Pain in Fibromyalgia – Is Your Microcirculation To Blame? – Health Rising – https://www.healthrising.org – by Cort Johnson | May 25, 2014
Exercise is highly recommended as an adjunct therapy in fibromyalgia.
Those of us with fibromyalgia know how extremely difficult this becomes. Our bodies seem to resist us with all their might and this article offers a possible explanation.
A 2010 review of exercise studies found that ‘slight to moderate’ intensity aerobic exercise sessions done two to three times a week worked best, and that appropriate levels of exercise result in improved fitness but only modestly improved pain. Continue reading
Can Pain Be Used to Treat Pain? — Pain News Network – By Jeanne McArdle – Apr 2019
“Can you cure pain with more pain?” was the provocative question posed last month by National Public Radio’s Invisibilia podcast, “The Fifth Vital Sign.”
The show features the story of Devyn, a 16-year old former gymnast living with chronic pain.
Devyn broke the end of her thighbone and required surgery, but the injury never fully healed and her pain was spreading. Continue reading