Most People Don’t Actually Feel Euphoric When They Take Opioids, Study Finds | Live Science – By Nicoletta Lanese – Staff Writer – Oct 2019
Finally, someone is willing to state the truth, one that goes against all the rabidly anti-opioid media hype:
Opioids jump-start the brain’s reward system, provoking a burst of pleasurable feelings along with a dizzying drug-induced high. At least that’s what scientists used to think.
But mounting research suggests that the average person doesn’t actually reach this euphoric state on opioids, particularly not the first time they try it.
Yet, this is exactly the kind of research that is not getting funded these days. Continue reading
Opinion | This Has Been the Best Year Ever – The New York Times – by Nicholas Kristof – Dec 2019
If you’re depressed by the state of the world, let me toss out an idea: In the long arc of human history, 2019 has been the best year ever.
The bad things that you fret about are true. But it’s also true that since modern humans emerged about 200,000 years ago, 2019 was probably the year in which
- children were least likely to die,
- adults were least likely to be illiterate and
- people were least likely to suffer excruciating and disfiguring diseases.
This is of small comfort to those of us with chronic pain, but at least someone somewhere is having a better life – and that is a genuine “good thing”, even if it isn’t affecting us directly. Continue reading
Humans Have Salamander-Like Ability to Regrow Cartilage in Joints –Duke Clinical Research Institute – Oct 2019
Here’s a promising development for one of the scourges of aging, osteoarthritis. Additionally, with EDS cartilage can be defective and deteriorate faster than the norm, so this could be very good news.
“Once cartilage is gone, it’s gone for good and there’s no replacement that we know of,” Luk said.
Contrary to popular belief, cartilage in human joints can repair itself through a process similar to that used by creatures such as salamanders and zebrafish to regenerate limbs, researchers at Duke Health found. Continue reading
Civil Rights Case Gives Hope to Pain Patients– By Richard Dobson, MD, Guest Columnist – Pain News Network – Feb 2019
Here’s a hopeful development: an example of a successful suit on the basis of discrimination under the Americans with Disability Act (ADA).
People with chronic disabling pain frequently complain that doctors discharge them from their practice because of the medications they take. Sometimes doctors refuse to accept patients who are taking opioid pain medications, even though the medications treat a legitimate medical condition.
There may be hope that such actions will be considered violations of the civil rights of patients. Continue reading
The Contribution of Prescribed and Illicit Opioids to Fatal Overdoses in Massachusetts, 2013-2015 – Oct 2019
Massachusetts is only an example of what we’d find in other states if they were more concerned with finding out what’s killing people who overdose. Instead, it’s often not tested adequately to find the real culprit because it’s already assumed that any sign of any opioid makes it a “prescription opioid overdose” to be added to those inflated numbers.
Opioid-related overdoses are commonly attributed to prescription opioids.
Whether true or not, our “public service” coroners just follow the path of least resistance and fall into the false confidence of their predetermined ideas. Continue reading
Health Officials Urge Caution in Reducing Opioids for Pain Patients – The New York Times – By Abby Goodnough – Oct 2019
In a newly published guide, federal health officials say doctors “should never abandon” pain patients and warn of acute withdrawal and other risks.
The Trump administration on Thursday instructed doctors to use more caution when taking chronic pain patients off opioid medications, a response to reports that many have been cutting off prescriptions too quickly, in some cases even dismissing patients from their practice.
Question: Why did we have to wait 3 1/2 years for this?
Answer: because no one wanted to know the results. Continue reading
Novel, ‘Non-Habit Forming’ Medication May Reduce Low Back Pain – Nancy A. Melville – Apr 2019
A novel, “non-habit-forming” neurosteroidappears to be effective and well tolerated in the treatment of chronic low back pain, new research suggests.
In a double-blind, randomized controlled trial of almost 100 Iraq/Afghanistan-era veterans, those treated with a pharmaceutical-grade tablet formulation of pregnenolone showed “significant and meaningful reductions” in low back pain intensity ratings at 6 weeks compared with their peers who received matching placebo, investigators report.
I’m excited about this because pregnenolone is an over-the-counter supplement available to us all.
UMN researchers study effect of chronic opioid therapy on pain and survival in sickle cell disease | EurekAlert! Science News – Apr 2019
Though this article is specifically about Sickle Cell Disease, it can be applied to many other kinds of chronic pain.
New UMN research recently published Blood Advances, Kalpna Gupta, PhD, Professor of Medicine, University of Minnesota Medical School, demonstrates the impact of opioids on the survival of humanized mouse models with sickle cell disease, compared to normal mice.
Sickle Cell Disease (SCD) affects millions of people throughout the world. The genetic disease worsens over time and can cause lifelong pain.
Given the often severe nature of the pain associated with SCD opioid use is a rule not an exception for treatment. Continue reading
The Link Between Misconceptions About Opioid Use Disorders and Current Policies – Clinical Pain Advisor – Aug 2019
Though the subject here is opioid addiction, I’m amazed and delighted to find this publication for medical professionals repudiating the assumed link between opioid prescribing and addiction.
The current opioid crisis is the third one observed in the United States. This latest trend is, however, the result of unusual factors and has had some unique effects.
Knee-jerk reactions to restrictions on opioid prescriptions have resulted in an increase in the narco-trafficking of heroin and fentanyl, and as the consumption of opioids shifted from oral intake to injections, hepatitis B and C and HIV infections have increased. Continue reading
First Generic Versions of Lyrica Approved by FDA – Pain Medicine News – based on a press release from the FDA – July 2019
The FDA approved the first generic versions of the pain medication pregabalin, the agency announced. It accepted multiple applications, granting approvals to nine manufacturers, including Teva Pharmaceuticals.
I have to wonder why *nine* manufacturers are lined up to sell this medication. Competition “should” lower the price, but that’s not how things work in pharmaceutical pricing. Continue reading