Brain imaging reveals dynamic changes caused by pain medicines | University of Michigan Health System – University of Michigan – 2013 (no longer available online in 2019. This is a repost with new relevance)
…the implication is that at least one factor in chronic pain can now be visualized by computer imaging. Pregabalin (Lyrica) soothes the insula, and the changes in insula activity and corresponding decreasing pain levels were made visible for the first time.
So far, we’ve only had static images of brains to compare those of people with chronic pain to those who are pain-free, but now we can compare the changes as they happen in a single individual. Continue reading
Can Interoception Improve the Pragmatic Search for Biomarkers in Psychiatry? – free full-text /PMC4958623/ – Jul 2016
This is another one of the articles I found about the extreme interoceptive sensitivity of people with hypermobility/EDS and how it is linked to anxiety.
Disrupted interoception is a prominent feature of the diagnostic classification of several psychiatric disorders. To examine the degree to which the scientific community has recognized interoception as a construct of interest,
we identified and individually screened all articles published in the English language on interoception and associated root terms in Pubmed, Psychinfo, and ISI Web of Knowledge. Continue reading
Neuroimaging and psychophysiological investigation of the link between anxiety, enhanced affective reactivity and interoception in people with joint hypermobility – May 2014
This study makes connections between the acute perception of our internal body states, which trigger excessive activation of our amygdala, with anxiety.
In lay terms, we are too sensitive and too responsive, thus unable to hold life’s rougher times at an arm’s distance. It’s as though we lack the protective barrier built into the “hardware” of most people to shield them from the extremes of their environment.
Objective: Anxiety is associated with increased physiological reactivity and also increased “interoceptive” sensitivity to such changes in internal bodily arousal. Continue reading
What Are Important Ethical Implications of Using Facial Recognition Technology in Health Care? – AMA Journal of Ethics – Nicole Martinez-Martin, JD, PhD
Applications of facial recognition technology (FRT) in health care settings have been developed to identify and monitor patients as well as to diagnose genetic, medical, and behavioral conditions.
The use of FRT in health care suggests the importance of informed consent, data input and analysis quality, effective communication about incidental findings, and potential influence on patient-clinician relationships.
Privacy and data protection are thought to present challenges for the use of FRT for health applications. Continue reading
Effective Treatment of Chronic Low Back Pain in Humans Reverses Abnormal Brain Anatomy and Function | Journal of Neuroscience – Free full-text article – May 2011
Though also not new, this study is a follow up on an earlier post: Brain abnormalities are Consequence Not Cause of pain (2009). The article below contains dozens of links to further information.
Chronic pain is associated with reduced brain gray matter and impaired cognitive ability.
In this longitudinal study, we assessed whether neuroanatomical and functional abnormalities were reversible and dependent on treatment outcomes. Continue reading
Neuroimaging for Chronic Pain: IASP Consensus Statement – by Tori Rodriguez, MA, LPC October 19, 2017 – repost of this critical article
health and disability insurance companies seek methods to confirm the pain status of beneficiaries to corroborate self-report, which is the current gold standard for pain assessment in clinical and research settings.
All parts of our health system (and its interface to the legal and financial systems) have difficulties with self-reported symptoms because they are all based on numerical values that are independently verifiable.
A blood test or x-ray taken by your doctor will not yield significant differences from the ones taken by your insurance company or lawyer, so these are seen as “factual evidence”. Continue reading
Can brainwaves be detected in lime Jell-O – “Dear Cecil” – Jun 2010
The Jell-O brainwave researcher was neurologist Adrian Upton, who conducted pioneering work on the electroencephalography of gelatin desserts starting in the 1960s.
Upton wasn’t trying to be a wise guy — he wanted to make a serious point about brain death, which became a matter of critical importance once life-support equipment made it possible to keep a body functioning even though its owner had checked out.
This made me think that if a patient’s brainwaves are the same as lime Jell-O, they should probably be considered dead, but what about other flavors? Continue reading
Scanning Dead Salmon in fMRI Machine Highlights Risk of Red Herrings – Wired.com – by Lexis Madrigal – Sep 2009
Here’s a humorous, but also dead serious (pardon the pun), study pointing out the HUGE problems with fMRI brain scans that supposedly tell us something about what we’re thinking or feeling.
Neuroscientist Craig Bennett purchased a whole Atlantic salmon, took it to a lab at Dartmouth, and put it into an fMRI machine used to study the brain. The beautiful fish was to be the lab’s test object as they worked out some new methods.
So, as the fish sat in the scanner, they showed it “a series of photographs depicting human individuals in social situations.” To maintain the rigor of the protocol (and perhaps because it was hilarious), the salmon, just like a human test subject, “was asked to determine what emotion the individual in the photo must have been experiencing.” Continue reading
Clinical evidence for cervical myelopathy due to Chiari malformation and spinal stenosis in a non-randomized group of patients with the diagnosis of fibromyalgia | SpringerLink – April 2004
While patients with fibromyalgia report symptoms consistent with cervical myelopathy, a detailed neurological evaluation is not routine.
We sought to determine if patients with fibromyalgia manifest objective neurological signs of cervical myelopathy.
I had never heard of this link between fibromyalgia and cervical myelopathy so this would be consistent with the theory that many fibromyalgia patients actually have EDS, which also leads to such types of cervical problems.
It seems this excellent information from over 10 years ago has been ignored by the medical establishment. Continue reading
AI can spot the pain from a disease some doctors still think is fake – By Olivia Goldhill – August 9, 2018
In the 16 years since Liptan had her illness [fibromyalgia] so summarily dismissed in 2002, there are still those who believe fibromyalgia isn’t “real.”
There’s no tissue damage that explains the pain fibromyalgia patients experience all over their body, and contemporary medicine struggles to treat and even accept an illness where pain seems to be rooted in the mind or brain, rather than a bodily injury.
Artificial intelligence, though, has the potential to make a diagnosis in minutes. Last year, researchers used machine learning to distinguish the brain scans of those with fibromyalgia from those without—with 93% accuracy. Continue reading