Study: Stopping Long-Term Opioid Prescriptions Associated With Veterans’ Deaths – Filter Magazine – By Staff – Mar 2020
For years, pain patient activists have been sounding the alarm about the consequences of abruptly halting people’s access to opioid analgesics…
And we have not just been whining and complaining about our increased “biopsychosocial” pain. The physical and mental impact of experiencing unrelieved, constant, chronic pain can be overwhelming. The danger of forced tapers is an extremely serious and urgent problem, which is increasingly…
…supported by much research. Continue reading
Misperceptions about the ‘Opioid Epidemic:’ Exploring the Facts – July 2019 – Pain Management Nursing
Thank goodness for nurses! In this lengthy document, they meticulously prove that the ‘Opioid Epidemic’ is a complete fabrication, hyped by anti-opioid activists and spread into our society and even our medical system despite reams of evidence to the contrary from science and government data.
This thoroughly referenced article itemizes and thoroughly debunks the anti-opioid misperceptions (if not outright lies) that have swept through the medical profession and corrupted clear, logical thinking about the rising rate of illicit drug overdoses (not from prescribed opioids).
This is the most sensible document I’ve ever read about the so-called “opioid crisis”. Supported by numerous scientific references, it makes all the arguments we pain patient advocates have been making for years. Continue reading
Most People Don’t Actually Feel Euphoric When They Take Opioids, Study Finds | Live Science – By Nicoletta Lanese – Oct 2019
Opioids are known to spark feelings of euphoria in users, but does everyone really share the same experience?
Opioids jump-start the brain’s reward system, provoking a burst of pleasurable feelings along with a dizzying drug-induced high. At least that’s what scientists used to think
But mounting research suggests that the average person doesn’t actually reach this euphoric state on opioids, particularly not the first time they try it. In fact, people who are not addicted to opioids may feel subjectively worse after taking the drug, according to cognitive neuroscientist Siri Leknes. Continue reading
Opioids Continue to Be Effective Long Term – Medscape – Fran Lowry – October 01, 2013
This is a good review with results that ring true in my experience,
Unfortunately, it’s fatally tainted by funding from Purdue.
An extensive literature review of studies evaluating the effectiveness of long-term opioid therapy in chronic noncancer pain (CNCP) concludes that the drugs continue to provide reliable and safe analgesia for 6 months or more.
“Due to FDA regulatory guidelines, most contemporary phase 3 randomized controlled trials of opioid analgesics for CNCP are 3 months long or less. Continue reading
Opioid Dose Tapering, Opioid Dependence, and Indications for Buprenorphine | Annals of Internal Medicine | American College of Physicians – September 2019
This article is significant only because its authors are all founding members of PROP, the group that initiated, escalated, inflamed, and essentially fabricated the whole issue with prescribed opioid medication:
- Roger Chou, MD;
- Jane Ballantyne, MD;
- Anna Lembke, MD.
I’m delighted to see even a tiny crack in the seemingly invincible force of opioid prohibition.
Pain Takes Significant Toll on Ovarian Cancer Survival, Study Shows – by Alberto Molano, PhD – Sep 2019
This study shows that constant pain is so damaging to health that it can shorten the life span. Any other symptom that led to such dismal outcomes would be treated aggressively and immediately as an emergency.
However, since pain is invisible and can only be determined by the patient themselves, it is doubted and left poorly treated, if at all. When pain medication is withheld from a patient, their constant pain can lead to an early death. This should be clear malpractice, but in today’s opioidphobic society doctors are pressured to do exactly that: leave pain poorly treated even though it’s detrimental to a patient’s health and welfare.
For the first time, scientists have found evidence that pain is an independent marker for overall survival in recurrent ovarian cancer, with women with pain living for significantly less time after their diagnosis than those without pain. Continue reading
UMN researchers study effect of chronic opioid therapy on pain and survival in sickle cell disease | EurekAlert! Science News – Apr 2019
Though this article is specifically about Sickle Cell Disease, it can be applied to many other kinds of chronic pain.
New UMN research recently published Blood Advances, Kalpna Gupta, PhD, Professor of Medicine, University of Minnesota Medical School, demonstrates the impact of opioids on the survival of humanized mouse models with sickle cell disease, compared to normal mice.
Sickle Cell Disease (SCD) affects millions of people throughout the world. The genetic disease worsens over time and can cause lifelong pain.
Given the often severe nature of the pain associated with SCD opioid use is a rule not an exception for treatment. Continue reading
Pain control methods in use and perceived effectiveness by patients with Ehlers-Danlos syndrome: a descriptive study. – PubMed – Disabil Rehabil. 2016;
The purpose of this study was to assess the pain control methods in use by patients who have Ehlers-Danlos Syndrome (EDS), a group of connective tissue disorders, and their perceived effectiveness
This descriptive study involved 1179 adults diagnosed with EDS who completed an anonymous on-line survey. The survey consisted of
- demographics information,
- the Patient Reported Outcomes Measurement Information System (PROMIS) Pain-Behavior,
- PROMIS Pain-Interference, and
- Neuro QOL Satisfaction with Social Roles and Activities scales, as well as a
- modified version of the Pain Management Strategies Survey. Continue reading
Mortality After Discontinuation of Primary Care-Based Chronic Opioid Therapy for Pain: a Retrospective Cohort Study. – PubMed – NCBI – J Gen Intern Med. – Aug 2019
Despite known risks of using chronic opioid therapy (COT) for pain, the risks of discontinuation of COT are largely uncharacterized.
These “risks of discontinuation of COT” are not “largely uncharacterized” but rather completely unstudied.
Pain patients being tapered are being used as guinea pigs because those who are restricting opioids have no idea what the results might be. Continue reading
Management of chronic pain in EDS – Nov 2018 – part 2
This post continues from the first part, with more detailed descriptions of various types of pain that arise from our tissue fragility and from consequences of related genetic changes.
3.1 Chronic pain and EDS overview (covered in previous post)
3.1.1 Musculoskeletal pain
Nociceptive, joint pain is usually the first manifestation of pain in EDS. Continue reading