Cannabis doesn’t give me pain relief as much as it gives me “mind relief”, but I know of some people who find it almost as effective as opioids. Below are a few articles explaining how this drug works and what side effects it may have:
Review of the neurological benefits of phytocannabinoids – free full-text /PMC5938896/ – 2018 Apr
Numerous physical, psychological, and emotional benefits have been attributed to marijuana since it was first reported in 2,600 BC (e.g., Chinese pharmacopoeia). The phytocannabinoids, cannabidiol (CBD), and delta-9-tetrahydrocannabinol (Δ9-THC), the most studied extracts from the cannabis sativa subspecies, include hemp and marijuana.
Recently, it has been successfully utilized as an adjunctive treatment for Continue reading
FDA Declares CBD ‘Beneficial,’ Wants Your Input ASAP – by Bruce Barcott – August 14, 2017
The United Nations is trying to figure out how to categorize cannabidiol (CBD), a non-psychoactive and medically beneficial cannabinoid contained in cannabis. And UN officials, through the US Food and Drug Administration (FDA), are asking for your help.
The FDA declared that
‘CBD has been shown to be beneficial.’
Now the agency needs your comments to back it up.
All those who have information on, or experience with, the use of CBD as a healing substance are encouraged to comment at this federal website. Continue reading
Cannabis May Reverse Aging Process In Brain: Here Are 5 Other Health Benefits Of Marijuana : HEALTH : Tech Times – May 2017, By Alexandra Lozovschi Tech Times
A recent study on mice revealed cannabis may improve memory later in life because of its protective effect on the brain.
The research showed that the key active ingredient found in marijuana, tetrahydrocannabinol (THC), could be used to reverse the decline in cognitive function, which typically comes with old age.
This latest health benefit associated with medical marijuana adds to a long list of curative properties, which have been amply described in numerous studies. Continue reading
Persistent Potentiation of the Analgesic Effects of Opioids by Delta-9Tetrahydrocannabinol (THC) in Nonhuman Primates – Apr 2017
Improving the analgesic effectiveness of opioids while also reducing the adverse effects is a major goal of pain research.
One approach to this problem has been to combine drugs such as cannabinoids with opioids to determine if this might reduce the dose of opioid required to produce analgesia.
In this experiment, male nonhuman primates (rhesus macaques) were administered a range of doses of THC in combination with cumulative doses of heroin to determine if the combinations produced greater analgesia than that observed with heroin alone.
Briefly, the animals were secured in standard primate ch airs, tails were shaved, and dipped in a mixed order in three different water temperatures (40 °, 50 °, and 55 °C) until the animal rapidly withdrew his tail, or 20 seconds elapsed. Continue reading
Low Dose Vaporized Cannabis Significantly Improves Neuropathic Pain – J Pain. 2013 Feb – free full-text PMC article
Even back in 2013, research had already shown that cannabis can be effective for pain relief,.
We conducted a double-blind, placebo-controlled, crossover study evaluating the analgesic efficacy of vaporized cannabis in subjects, the majority of whom were experiencing neuropathic pain despite traditional treatment.
Thirty-nine patients with central and peripheral neuropathic pain underwent a standardized procedure for inhaling either medium dose (3.53%), low dose (1.29%), or placebo cannabis with the primary outcome being VAS pain intensity Continue reading
Low-dose cannabinoid THC restores memory and learning in old mice – Medical News Today – by Catharine Paddock PhD – May 2017
A new study found that while a low dose of the cannabinoid delta-9-tetrahydrocannabinol caused young mice to perform worse in learning and memory tasks, it restored age-related learning and memory decline in old mice.
However, the researchers warn than more work must be done before it can be said that the cannabis compound might reverse cognitive decline in elderly humans
Cannabinoids such as delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are a class of more than 100 psychoactive, or mind-altering, compounds that are found in the cannabis, or marijuana, plant. They exert a powerful effect because they interact with cannabinoid receptors in the brain. Continue reading
Comparison of Cannabinoid Concentrations in Plasma, Oral Fluid and Urine in Occasional Cannabis Smokers After Smoking Cannabis Cigarette – 2016
This is the gold standard for scientific studies and it shows that THC concentrations in urine or saliva cannot determine plasma THC levels which could indicate the level of inebriation from cannabis.
Purpose. A randomized cross-over, double blind placebo controlled study of smoked cannabis was carried out on occasional cannabis smokers.
Conclusion. Prediction of plasma THC concentration from THC oral fluid concentration or from THC-COOH urinary concentrations is not feasible due to the large variations observed.
Dosing with Edibles – www.medicann.com – Feb 2017
Edibles are a great option to administer medicine, but it’s important to know that the body responds differently to each mode of administration.
Consider these factors when taking edibles as opposed to smoking cannabis:
1) The effects of ingesting a cannabis infused edible takes longer to begin,
2) The effects can be stronger and more intense, and, 3) The effects can last longer.
The differences derive from how the body responds to cannabis when it is smoked as opposed to when it is ingested as an edible. Continue reading
Health Effects of Marijuana and Cannabis-Derived Products Presented in New Report – Jan. 12, 2017
In this paper, it’s clear the researchers are desperately trying to reach negative conclusions, even if they must resort to stating only that they “have found limited evidence to suggest that…”.
This sentence wording associates the word “evidence” with the various impairments they then list that may or may not be associated with cannabis, let alone be caused by it.
Nearly 100 Conclusions on the Health Effects of Marijuana and Cannabis-Derived Products Presented in New Report; One of the Most Comprehensive Studies of Recent Research on Health Effects of Recreational and Therapeutic Use of Cannabis and Cannabis-Derived Products
A new report from the National Academies of Sciences, Engineering, and Medicine offers a rigorous review of scientific research published since 1999 about what is known about the health impacts of cannabis and cannabis-derived products – such as marijuana and active chemical compounds known as cannabinoids – ranging from their therapeutic effects to their risks for causing certain cancers, diseases, mental health disorders, and injuries. Continue reading