Tag Archives: supplements

Kratom and Chronic Pain

Here is a list of information, news, and research articles on Kratom, collected by Inspire.com user “Seshet”:

Kratom and Chronic Pain

Info Sites:

News/General Articles:   Continue reading

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Baking soda to combat autoimmune disease

Drinking baking soda could be an inexpensive, safe way to combat autoimmune disease: A daily dose of baking soda may help reduce the destructive inflammation of autoimmune diseases like rheumatoid arthritis, scientists say. — ScienceDaily – April 2018

A daily dose of baking soda may help reduce the destructive inflammation of autoimmune diseases like rheumatoid arthritis, scientists say.

They have some of the first evidence of how the cheap, over-the-counter antacid can encourage our spleen to promote instead an anti-inflammatory environment that could be therapeutic in the face of inflammatory disease, Medical College of Georgia scientists report in the Journal of Immunology.   Continue reading

The health benefits of coffee

The latest scoop on the health benefits of coffee – Harvard Health Blog – Harvard Health Publishing – September 25, 2017 – Robert H. Shmerling, MD – Faculty Editor, Harvard Health Publishing

What a difference a few years can make. Not long ago, I was learning about the dangers of coffee — how it could raise your blood pressure, make your heart race, impair sleep, and maybe even cause cancer.

Now, the World Health Organization (WHO) is taking coffee off the possible carcinogen list. And there’s increasing evidence that coffee might actually be good for you. So good that doctors might begin recommending it.

I hope to read an article like this about opioids someday when all the supposed negatives are shown to be the results of poorly designed and/or executed studies.  Continue reading

Caffeine and Opioid Use Beneficial for Chronic Pain

Caffeine and Opioid Use Beneficial for Fibromyalgia-Like Chronic Pain By Brandon May – September 15, 2017

This headline is a bit misleading because opioids were only studied in tandem with caffeine and not separately recommended.

I drink a lot of coffee (even more now that I know it’s healthy) most of the day, so my opioids are usually combined with caffeine. I guess I stumbled onto a  winning combination.

Caffeine is associated with lower pain catastrophizing, greater physical function, and lower pain interference in patients taking opioids to manage fibromyalgia pain, according to results from a survey-based study published in the Journal of Pain Research.  Continue reading

Could Nicotine Help Protect The Aging Brain?

Could Nicotine Help Protect The Aging Brain? – Neuroscience News – September 21, 2016

Texas A&M research shows how this component of cigarettes might actually be beneficial on its own. …according to research at Texas A&M, it turns out the nicotine itself—when given independently from tobacco—could help protect the brain as it ages, and even ward off Parkinson’s or Alzheimer’s disease.

Ursula Winzer-Serhan, PhD, an associate professor at the Texas A&M College of Medicine, and her collaborators found that nicotine’s ability to be neuroprotective may be partly due to its well-known ability to suppress the appetite.   Continue reading

MSM, Strenuous Exercise, Cytokine Release

The Influence of Methylsulfonylmethane on Inflammation-Associated Cytokine Release before and following Strenuous Exercise – Oct 2016 – free full-text PMC5097813

Inflammation is associated with strenuous exercise and methylsulfonylmethane (MSM) has been shown to have anti-inflammatory properties.

Methods. A total of 40 men began the study and completed testing.

Subjects were healthy, physically active, and nonsmokers and did not have any cardiovascular or metabolic disorders.

Physically active men were supplemented with either placebo or MSM (3 grams per day) for 28 days before performing 100 repetitions of eccentric knee extension exercise.   Continue reading

MSM, Oxidative Stress, Muscle Damage, and Pain

Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial  – free full-text PMC5521097 – 2017 Jul

Oxidative stress and muscle damage occur during exhaustive bouts of exercise, and many runners report pain and soreness as major influences on changes or breaks in training regimens, creating a barrier to training persistence.

Methylsulfonylmethane (MSM) is a sulfur-based nutritional supplement that is purported to have pain and inflammation-reducing effects.

To investigate the effects of MSM in attenuating damage associated with physical exertion, this randomized, double-blind, placebo-controlled study evaluated the effects of MSM supplementation on exercise-induced pain, oxidative stress and muscle damage.   Continue reading

Alcohol Risky but Effective Pain Reliever

Study Finds Alcohol Risky but Effective Pain Reliever — Pain News Network – May 03, 2017/ Pat Anson

The dangers of alcohol are well known – from drunk driving to health, work and social problems. But with opioid painkillers becoming harder to obtain, some chronic pain sufferers are turning to alcohol to dull their pain.

And now there’s research to back them up.

In an analysis of 18 studies published in the Journal of Pain, British researchers found “robust evidence” that a few drinks can be an effective pain reliever.

“Findings suggest that alcohol is an effective analgesic that delivers clinically-relevant reductions in ratings of pain intensity, which could explain alcohol misuse in those with persistent pain despite its potential consequences for long-term health,” wrote lead author Trevor Thompson, PhD, University of Greenwich.

Thompson and his colleagues say a blood-alcohol content of .08% — which meets the legal definition of drunk driving in many U.S. states – produces a “moderate to large reduction in pain intensity” and a small elevation in pain threshold.

Despite the risks involved, some pain sufferers are turning to alcohol as a last resort and mixing it with pain relievers – a potentially lethal combination.

My doctor took me off all opioids last year and put me on Effexor, Naproxen, and extended relief Tylenol. It barely touches my pain so I am also drinking each night to help dull the pain,” one patient told us.

“The doctor tried gabapentin but I ended up with an overnight stay in the hospital due to a bad reaction to the medication,” another patient said. “I’m now using alcohol nightly to help me sleep along with high amounts of Naproxen and Tylenol daily.”

“I suffer extreme back and neck pain. Since they no longer prescribed painkillers I started drinking and find it is helpful.

How much is too much?

According to the Mayo Clinic, moderate alcohol consumption for healthy adults means up to one drink a day for women of all ages and men older than age 65, and up to two drinks a day for men age 65 and younger.

See also:

L-carnitine for fatigue in patients with hypothyroidism

L-carnitine supplementation for the management of fatigue in patients with hypothyroidism on levothyroxine treatment: a randomized, double-blind, placebo-controlled trial– Endocrine Journal – 2016 – free full-text

Hypothyroid patients experience fatigue-related symptoms despite adequate thyroid hormone replacement.

Thyroid hormone plays an essential role in carnitine-dependent fatty acid import and oxidation.

We investigated the effects of L-carnitine supplementation on fatigue in patients with hypothyroidism.   Continue reading

Potential Benefits of Vit D for Muscles & Fatigue

Below are links to 5 full-text PMC articles from PubMed on the potential benefits of Vitamin D. 

This vitamin has shown inconsistent results in studies, but because it’s relatively harmless except in very high doses, it may be worth a try.

Muscles:

Continue reading