EDS and Anesthetics

Here’s a compilation of information and links from our tireless EDS champion, Shani Weber:

We have an odd relationship to topical anesthetics like lidocaine. For some of us, they don’t work. For others of us, it takes a lot more than usual for them to work, but once that threshold is reached, the topicals last longer than usual.

Those with EDS frequently have problems with local anesthesia as well as general anesthesia. This difference is mentioned briefly in “Pharmacological Considerations in Ehlers-Danlos Syndrome”: http://www.ednf.org/medical-professionals/pharmacological-considerations-eh lers-danlos-syndrom

The tendency for those with EDS not responding to local anesthetics is included in the Dentistry Medical Resource Guide: http://www.ednf.org/dentistry-resource-guide

and also in this medical journal article “Local anaesthetic failure in joint hypermobility syndrome” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079398/

“Do local/dental anesthetics fail for you…patients with EDS are resistant to lidocaine…” http://www.mdjunction.com/forums/ehlers-danlos-syndrome-discussions/general -support/2299144-do-localdental-anesthetics-fail-for-you

“The response to local anaesthetics (EMLA-cream) as a clinical test to diagnose between hypermobility and Ehlers Danlos type III syndrome.” http://www.ncbi.nlm.nih.gov/pubmed/2068541

“ Anesthesia recommendations for patients suffering from Ehlers-Danlos Syndrome” https://www.orpha.net/data/patho/Pro/en/Ehlers_Danlos_En.pdf


“Recommendations for anesthesia and perioperative management in patients with Ehlers-Danlos syndrome(s)” http://www.ojrd.com/content/9/1/109


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