Visceroptosis and the Ehlers-Danlos Syndrome

Visceroptosis and the Ehlers-Danlos Syndrome – X-rays – free full-text /PMC5773269/ – 2017 Nov

This is a detailed story, abundantly illustrated with abdominal X-rays, showing how the lax tissues of EDS may not be strong enough and can allow our organs to sink to the bottom of the pelvis. 

Click on the link to see the full study – the X-rays of this man’s abdomen are spectacularly scary.

The case of a patient with visceroptosis and Ehlers-Danlos syndrome hypermobility type (RDS-HT) is reported here. The literature on this unusual but probably under-recognized complication is reviewed.   Continue reading


NHS to stop ‘ineffective’ treatments

NHS to stop ‘ineffective’ treatments – June 2018

Officials are to discuss proposals to stop or reduce 17 routine procedures deemed to be “ineffective or risky”.

The treatment will be offered only if it is judged to be of “compelling” benefit and there are no alternatives.

NHS England said the move would affect about 100,000 people every year and free up an estimated £200m.  Continue reading

Pain When Immune System Attacks Its Own Proteins

When the Immune System Attacks Its Own Proteins, Pain Can Emerge – RELIEF: PAIN RESEARCH NEWS, INSIGHTS AND IDEAS – July 2018 – By Nathan Fried

For decades, doctors have been puzzled why some patients with entirely different autoimmune disorders share pain from nerve injury (neuropathic pain) in common.

Recently, a clue emerged when researchers found that the immune system in many of these patients makes an autoantibody—an antibody that attacks the body’s own proteins—against CASPR2. CASPR2 is a protein found in the nervous system.   Continue reading

Fentanyl Deaths Double in 10 States, CDC Reports

Fentanyl Deaths Double in 10 States, CDC Reports | Medpage Today – by Judy George, Contributing Writer, MedPage Today July 12, 2018

Unfortunately, this new data will fall on deaf ears, even in-house. The same agency that counts all these deaths from illicit drugs remains stubbornly fixated on restricting prescription opioids.

The number of opioid overdose deaths in which fentanyl was detected in 10 states doubled during the first half of 2017 compared with the second half of 2016, according to the CDC’s Mortality and Morbidity Weekly Report — putting numbers to a trend already known qualitatively.

The number of deaths from carfentanil nearly doubled, too.   Continue reading

Cancer pain management and the opioid crisis

Cancer pain management and the opioid crisis in America: How to preserve hard-earned gains in improving the quality of cancer pain management. – PubMed – NCBI – June 2018

Cancer pain remains a feared consequence of the disease and its treatment. Although prevalent, cancer pain can usually be managed through the skillful application of pharmacologic and nonpharmacologic interventions.

Come on, just say it: “cancer pain can usually be managed through opioids.”   Continue reading

Nora Volkow on Rx opioids, chronic pain and ‘hype’

Nora Volkow on prescription opioids, chronic pain and ‘hype’ – Opioid Watch – Nonprofit News from The Opioid Research Institute – July 2018

Research psychiatrist Nora Volkow, MD—the director of the National Institute on Drug Abuse for the past 15 years—is one of the world’s foremost authorities on addiction. Her pioneering work with brain imaging has changed society’s understanding of the phenomenon.

By showing how addictive drugs alter the brain’s chemistry, she helped prove that addiction was a chronic disease rather than a moral failing.

What follows is part 1 of a two-part interview, which was conducted by email. All links in her answers are to supporting references Volkow provided.   Continue reading

Unintended Consequences Of Addressing Opioid Crisis

Healthcare Pros Talk Unintended Consequences Of Addressing Opioid Crisis | The Fix – By Kelly Burch – 06/25/18

I shared my own thoughts about so-called “unintended consequences” on the National Pain Report, “CDC Opioid Prescribing Guideline: Unintentional Consequences?

The opioid epidemic has drawn more political and media attention than any other public health crisis in recent memory, but healthcare professionals say that the focus on preventing opioid-related deaths is having unintended consequences for patients dealing with other conditions including cancer, chronic pain and other forms of substance use disorder.

One of the biggest concerns is that patients are being taken off their opioids too quickly, which can increase physical symptoms of withdrawal and leave patients feeling overwhelmed by the idea of quitting.  Continue reading

Managing Cancer Pain in the Era of an Opioid Crisis

Managing Cancer Pain in the Era of an Opioid Crisis by Roxanne Nelson, BSN, RN – June 13, 2018

Opioids are commonly used to treat pain in patients with cancer, especially in those with advanced disease.

But in the era of the opioid epidemic and crisis, there are growing questions and concerns over how to appropriately manage cancer-related pain and avoid misuse and overuse of these agents.

How sad, that cancer patients are now being tortured just like we folks with chronic pain are.    Continue reading

Work-Enabling Opioid Management

Work-Enabling Opioid Management. – PubMed – NCBI – Aug 2017

OBJECTIVE: This study describes the relationship between opioid prescribing and ability to work.

METHODS: The opioid prescription patterns of 4994 claimants were studied.

This group is certainly large enough to draw conclusions from – and the scientifically proven conclusion is what we pain patients already know…   Continue reading

FDA seeking ‘right balance’ for opioid regulations

FDA seeking ‘right balance’ in regulating opioid prescriptions | BioPharma Dive By Rebecca Pifer Published July 10, 2018

Food and Drug Administration chief Scott Gottlieb reaffirmed in a statement Monday the agency’s commitment to finding the “right balance” between reducing the U.S. rate of opioid addiction and providing access to legitimate patients, for whom these medications can be lifesaving.

He had strong words for practitioners regarding their role in helping spur the opioid epidemic. “The roots of this crisis are embedded in the practice of medicine, and prescribing practices that were at times too cavalier,” Gottlieb said.

No, they are not. The “roots” of this crisis are the skyrocketing rates of addiction. And the problem is expanding much farther than just opioids, with use of and overdoses from drugs like meth and cocaine rising.  Continue reading